mTOR inhibitor

ChEBI CHEBI:68481
Associated conditions

Datasets

Paper Phenotype Condition Medium Collection Tested mutants Data Details
Chan TF~Zheng XF, 2000 growth (streaks on agar) sirolimus [25 nM] YPD hap a ~2,216 Discrete
Xie MW~Huang J, 2005 growth (colony size) sirolimus [10 nM] YPD + DMSO [0.1%] hap a/het 5,784 Quantitative
Xie MW~Huang J, 2005 growth (colony size) sirolimus [30 nM] YPD + DMSO [0.1%] hap a/het 5,784 Quantitative
Parsons AB~Boone C, 2004 growth (colony size) sirolimus [0.015 ug/ml] YPD hap a ~4,700 Discrete
Neklesa TK~Davis RW, 2008 growth (relative abundance in pooled culture) sirolimus [7.5 ng/ml] YPD hom ~4,757 Discrete
Parsons AB~Boone C, 2006 growth (relative abundance in pooled culture) sirolimus [5.5 pM] hap a 4,111 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) sirolimus [4.88 nM], time [o/n + 20 gen] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) sirolimus [5 nM], time [o/n + 20 gen] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) sirolimus [6 nM], time [o/n + 20 gen] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) sirolimus [9 nM], time [5 gen] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) sirolimus [9 nM], time [o/n + 10 gen] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) sirolimus [9 nM], time [o/n + 5 gen] hom 4,742 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) sirolimus [1 nM] YPD hom 4,516 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) sirolimus [0.2 nM] YPD hom 4,516 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) sirolimus [0.5 nM] YPD hom 4,516 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) sirolimus [0.8 nM] YPD hom 4,516 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) sirolimus [4.00 nM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) sirolimus [2.00 nM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) sirolimus [362.00 pM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) sirolimus [1.00 nM] hom 4,810 Quantitative
Dudley AM~Church GM, 2005 growth (spot assay) sirolimus [0.1 ug/ml] YPD hom 4,621 Discrete
Neklesa TK~Davis RW, 2009 TORC1 activity (Dal80pr-GFP) sirolimus [20 ng/ml] hom ~5,100 None
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) sirolimus [0.2 nM] YPD het 5,782 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) sirolimus [0.5 nM] YPD het 5,782 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) sirolimus [0.8 nM] YPD het 5,782 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) sirolimus [4.88 nM], time [o/n + 20 gen] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) sirolimus [5 nM], time [o/n + 20 gen] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) sirolimus [6 nM], time [o/n + 20 gen] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) sirolimus [9 nM], time [o/n + 20 gen] het 5,686 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) sirolimus [362.00 pM] het 855 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) sirolimus [1.00 nM] het 818 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) sirolimus [4.00 nM] het 881 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) sirolimus [2.00 nM] het 880 Quantitative
Dobzinski N~Gerst JE, 2015 transport to vacuoles (GFP-Yif1) sirolimus [200 ug/L], temperature [26ÂșC] SC - Ura hap a 4,885 Discrete