immunosuppressive agent

ChEBI CHEBI:35705
Associated conditions

Datasets

Papers Phenotype Conditions Collection Tested mutants Data Details
Chan TF~Zheng XF, 2000 growth (streaks on agar) rapamycin [25 nM] hap a ~2,216 Discrete
Xie MW~Huang J, 2005 growth (colony size) rapamycin [10 nM] hap a/het 5,784 Quantitative
Xie MW~Huang J, 2005 growth (colony size) rapamycin [30 nM] hap a/het 5,784 Quantitative
Desmoucelles C~Daignan-Fornier B, 2002 growth (undefined) mycophenolic acid [30-100 mg/L] hap alpha 4,775 Discrete
Chamilos G~Kontoyiannis DP, 2008 growth (MIC) gliotoxin [0.03-16 ug/ml] hap a 4,588 Quantitative only for hits
Parsons AB~Boone C, 2004 growth (colony size) cyclosporin A [100 ug/ml] hap a ~4,700 Discrete
Parsons AB~Boone C, 2004 growth (colony size) rapamycin [0.015 ug/ml] hap a ~4,700 Discrete
Barreto L~Arino J, 2011 growth (spot assay) spermine [0.6-0.7 mM] hap a ~4,900 None
Giaever G~Davis RW, 2004 growth (relative abundance in pooled culture) methotrexate [125 uM], time [overnight + 20 generations] het 5,722 Quantitative
Neklesa TK~Davis RW, 2008 growth (relative abundance in pooled culture) rapamycin [7.5 ng/ml] hom ~4,757 Discrete
Parsons AB~Boone C, 2006 growth (relative abundance in pooled culture) rapamycin [5.5 pM] hap a 4,111 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) chlorambucil [15.63 uM], time [overnight + 20 generations] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 20 generations], chlorambucil [250 uM] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 20 generations], chlorambucil [500 uM] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 20 generations], melphalan [250 uM] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) melphalan [500 uM], time [overnight + 20 generations] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 20 generations], melphalan [2 mM] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) methotrexate [250 uM], time [overnight + 20 generations] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 20 generations], mycophenolic acid [125 uM] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) myriocin [0.2 ug/ml], time [5 generations] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) rapamycin [4.88 nM], time [overnight + 20 generations] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 20 generations], rapamycin [5 nM] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) rapamycin [6 nM], time [overnight + 20 generations] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) rapamycin [9 nM], time [5 generations] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [5 generations], methotrexate [500 uM] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 10 generations], rapamycin [9 nM] hom 4,742 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 5 generations], rapamycin [9 nM] hom 4,742 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) ascomycin [100 uM] hom 4,518 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) methotrexate [200 uM] hom 4,565 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) rapamycin [1 nM] hom 4,516 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) gliotoxin [8.723 uM] hom 4,524 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) mycophenolic acid [70 uM] hom 4,547 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) rapamycin [0.2 nM] hom 4,516 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) rapamycin [0.5 nM] hom 4,516 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) rapamycin [0.8 nM] hom 4,516 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) mycophenolic acid [100 uM] hom 4,543 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) mycophenolic acid [120 uM] hom 4,548 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) tacrolimus [29.80 uM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) rapamycin [4.00 nM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) rapamycin [2.00 nM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) myriocin [605.00 nM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) rapamycin [362.00 pM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) methotrexate [289.60 uM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) melphalan [456.52 uM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) spermine [47.74 uM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) mycophenolic acid [32.93 uM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) rapamycin [1.00 nM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) mycophenolic acid [18.85 uM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) tacrolimus [100.00 uM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) auranofin [4.32 uM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) leflunomide [42.06 uM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) methotrexate [400.00 uM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) gliotoxin [8.33 uM] hom 4,810 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) mycophenolic acid [780.42 nM] hom 4,810 Quantitative
Brown JA~Brown JM, 2006 growth (relative abundance in pooled culture) arabinofuranosyl cytidine [400 uM] hom 4,283 Quantitative
Brown JA~Brown JM, 2006 growth (relative abundance in pooled culture) melphalan [800 uM] hom 4,283 Quantitative
Lum PY~Shoemaker DD, 2004 growth (relative abundance in pooled culture) minimal complete [standard], arabinofuranosyl cytidine [500 ug/ml] het 3,503 Quantitative only for hits
Lum PY~Shoemaker DD, 2004 growth (relative abundance in pooled culture) minimal complete [standard], gliotoxin [3 ug/ml] het 3,503 Quantitative only for hits
Lum PY~Shoemaker DD, 2004 growth (relative abundance in pooled culture) minimal complete [standard], methotrexate [12.5 ug/ml] het 3,503 Quantitative only for hits
Lum PY~Shoemaker DD, 2004 growth (relative abundance in pooled culture) minimal complete [standard], thalidomide [1 mg/ml] het 3,503 Quantitative only for hits
Dudley AM~Church GM, 2005 growth (spot assay) mycophenolic acid [20 ug/ml] hom 4,621 Discrete
Dudley AM~Church GM, 2005 growth (spot assay) rapamycin [0.1 ug/ml] hom 4,621 Discrete
Neklesa TK~Davis RW, 2009 TORC1 activity (Dal80pr-GFP) sirolimus [20 ng/ml] hom ~5,100 None
Giaever G~Davis RW, 2004 growth (relative abundance in pooled culture) methotrexate [250 uM], time [overnight + 20 generations] het 5,722 Quantitative
Giaever G~Davis RW, 2004 growth (relative abundance in pooled culture) time [overnight + 20 generations], methotrexate [500 uM] het 5,722 Quantitative
Singh-Babak SD~Cowen LE, 2012 growth (relative abundance in pooled culture) time [20 generations], cyclosporin A [10 uM] het 1,069 Quantitative
Singh-Babak SD~Cowen LE, 2012 growth (relative abundance in pooled culture) cyclosporin A [10 uM], time [5 generations] hom 4,416 Quantitative
Singh-Babak SD~Cowen LE, 2012 growth (relative abundance in pooled culture) time [20 generations], cyclosporin A [10 uM], micafungin [0.045 ug/ml] het 1,069 Quantitative
Singh-Babak SD~Cowen LE, 2012 growth (relative abundance in pooled culture) time [5 generations], micafungin [0.045 ug/ml], cyclosporin A [10 uM] hom 4,416 Quantitative
Lebesgue N~Lemeer S, 2017 growth (colony size) myriocin [0.05 ug/ml] 5,369 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) ascomycin [100 uM] het 5,801 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) methotrexate [200 uM] het 5,824 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) mycophenolic acid [70 uM] het 5,795 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) rapamycin [0.2 nM] het 5,782 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) rapamycin [0.5 nM] het 5,782 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) rapamycin [0.8 nM] het 5,782 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) mycophenolic acid [100 uM] het 5,798 Quantitative
Hoepfner D~Movva NR, 2014 growth (relative abundance in pooled culture) mycophenolic acid [120 uM] het 5,802 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) methotrexate [250 uM], time [overnight + 20 generations] het 5,720 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 20 generations], methotrexate [500 uM] het 5,720 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 20 generations], mycophenolic acid [125 uM] het 5,720 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) rapamycin [4.88 nM], time [overnight + 20 generations] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 20 generations], rapamycin [5 nM] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) rapamycin [6 nM], time [overnight + 20 generations] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) methotrexate [125 uM], time [overnight + 20 generations] het 5,720 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) chlorambucil [800 uM], time [overnight + 20 generations] het 5,720 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) chlorambucil [1 mM], time [overnight + 20 generations] het 5,720 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) arabinofuranosyl cytidine [2 mM], time [overnight + 20 generations] het 5,720 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) melphalan [200 uM], time [overnight + 20 generations] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) leucovorin [500 uM], time [overnight + 20 generations], methotrexate [125 uM] het 5,720 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) 5-fluoro-uracil [38.4 uM], time [overnight + 20 generations], methotrexate [125 uM] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 20 generations], 5-fluoro-uracil [19.2 uM], methotrexate [125 uM] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 20 generations], 5-fluoro-uracil [76.8 uM], methotrexate [125 uM] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) leucovorin [500 uM], methotrexate [250 uM], time [overnight + 20 generations] het 5,720 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) methotrexate [250 uM], time [overnight + 20 generations], 5-fluoro-uracil [19.2 uM] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 20 generations], methotrexate [250 uM], 5-fluoro-uracil [76.8 uM] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) 5-fluoro-uracil [38.4 uM], methotrexate [250 uM], time [overnight + 20 generations] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 20 generations], leucovorin [500 uM], methotrexate [500 uM] het 5,720 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 20 generations], 5-fluoro-uracil [76.8 uM], methotrexate [500 uM] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) 5-fluoro-uracil [38.4 uM], methotrexate [500 uM], time [overnight + 20 generations] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) methotrexate [500 uM], time [overnight + 20 generations], 5-fluoro-uracil [19.2 uM] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) time [overnight + 20 generations], mycophenolic acid [500 uM] het 5,720 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) myriocin [0.15 ug/ml], time [overnight + 20 generations] het 5,686 Quantitative
Hillenmeyer ME~Giaever G, 2008 growth (relative abundance in pooled culture) rapamycin [9 nM], time [overnight + 20 generations] het 5,686 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) tacrolimus [29.80 uM] het 931 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) myriocin [605.00 nM] het 880 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) rapamycin [362.00 pM] het 855 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) mycophenolic acid [32.93 uM] het 1,052 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) rapamycin [1.00 nM] het 818 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) leflunomide [42.06 uM] het 815 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) mycophenolic acid [780.42 nM] het 962 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) rapamycin [4.00 nM] het 881 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) rapamycin [2.00 nM] het 880 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) methotrexate [289.60 uM] het 1,052 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) melphalan [456.52 uM] het 1,052 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) spermine [47.74 uM] het 839 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) mycophenolic acid [18.85 uM] het 818 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) tacrolimus [100.00 uM] het 818 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) auranofin [4.32 uM] het 815 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) methotrexate [400.00 uM] het 815 Quantitative
Lee AY~Giaever G, 2014 growth (relative abundance in pooled culture) gliotoxin [8.33 uM] het 1,016 Quantitative
Dobzinski N~Gerst JE, 2015 transport to vacuoles (GFP-Yif1) sirolimus [200 ug/L], minimal complete -Ura [standard], temperature [26ÂșC] hap a 4,885 Discrete